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Ep 380: How Age Really Affects Female Fertility In Perimenopause w/ Jaime Knopeman

Season #3

Fertility is often treated like a guarantee until it isn’t.

I wanted this conversation because I see so many women doing everything “right” in life, only to feel blindsided when fertility doesn’t align with their timeline. We talk about why fertility is not one thing, how egg quality and quantity change over time, and why having regular cycles doesn’t always mean fertility is intact. We also unpack what egg freezing actually offers, who it’s for, and how modern fertility care has expanded options far beyond what most of us were taught. 

I’m joined by Dr. Jaime Knopeman, often called the “queen of egg freezing,” who brings decades of experience helping women navigate fertility decisions with honesty and compassion.

If fertility has ever felt confusing, stressful, or quietly heavy, tune in and you’ll walk away feeling more informed, grounded, and supported

Episode Timeline: 

00:00 – Episode Preview

01:31 – Podcast Intro

02:05 – Queen of Egg Freezing

03:12 – Career vs Fertility Timing

03:56 – Ideal Egg Freezing Age

05:24 – Egg Quality Matters Most

06:19 – Pregnancy After Menopause

07:19 – Be Your Own Egg Donor

08:44 – Why Egg Freezing Surged

10:02 – Fertility at 40 Myth

11:43 – Lifestyle Guilt Explained

15:06 – IVF Lab Quality Matters

18:40 – IVF Emotional Toll

21:33 – Fertility Myths Unlearned

23:04 – Fertility Is Inefficient

24:59 – Own Your Fertility Book

28:20 – Motherhood Looks Different

32:16 – Where to Find Dr. Jamie



About Dr. Jaime Knopman: 

 

Is a double board-certified reproductive endocrinologist, Director of Fertility Preservation at CCRM Fertility New York, and author of the forthcoming book Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future, (Countryman Press, Jan 13th, 2026). Known nationally as the “Queen of Egg Freezing,” Dr. Knopman’s approach to reproductive care is both scientific and radically human; she's on a mission to help women understand the real biological and hormonal shifts that affect fertility, including the one almost no one talks about: perimenopause.

 

Connect with Dr. Jaime Knopman: 



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